| Bioactivity | Monoethylglycinexylidide (MEGX) hydrochloride is a metabolite of Lidocain (HY-B0185) via oxidative N-deethylation of Lignocaine by liver cytochrome P-450 enzymes in the liver. Monoethylglycinexylidide has proven to be a highly sensitive indicator of hepatic dysfunction, especially in the field of liver transplantation[1][2]. |
| Name | Monoethylglycinexylidide hydrochloride |
| CAS | 7729-94-4 |
| Formula | C12H19ClN2O |
| Molar Mass | 242.75 |
| Appearance | Solid |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
| Reference | [1]. Huang YS, et al. Measuring lidocaine metabolite--monoethylglycinexylidide as a quantitative index of hepatic function in adults with chronic hepatitis and cirrhosis. J Hepatol. 1993 Aug;19(1):140-7. [2]. Esen F, et al. Monoethylglycinexylidide (MEGX) as an early predictor of liver dysfunction in severe sepsis. Critical Care, 1997, 1(Suppl 1):P083. |
Monoethylglycinexylidide hydrochloride
CAS: 7729-94-4 F: C12H19ClN2O W: 242.75
Monoethylglycinexylidide (MEGX) hydrochloride is a metabolite of Lidocain (HY-B0185) via oxidative N-deethylation of Lig
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