| Bioactivity | Monocrotaline is an pyrrolizidine alkaloid extracted from the seeds of the Crotalaria pallida plant to induce pulmonary hypertension in rodents. |
| Invitro | Monocrotaline (MCT) is an 11-membered macrocyclic pyrrolizidine alkaloid (PA) derived from the seeds of the Crotalaria pallida plant[1]. Monocrotaline a natural ligand exhibits dose-dependent cytotoxicity with potent antineoplastic activity. The in vitro cytotoxicity of monocrotaline is proved at IC50 24.966 µg/mL and genotoxicity at 2 X IC50 against HepG2 cells[2]. |
| Name | Monocrotaline |
| CAS | 315-22-0 |
| Formula | C16H23NO6 |
| Molar Mass | 325.36 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, sealed storage, away from moisture and light *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light) |