Bioactivity | Mono(3-carboxypropyl) phthalate-d4 (MCPP-d4) is a deuterium labeled Mono(3-carboxypropyl) phthalate (HY-133673). Mono(3-carboxypropyl) phthalate (MCPP) is a metabolite of Di-n-octyl phthalate. Di-n-octyl phthalate (DnOP) is a plasticizer used in polyvinyl chloride plastics, cellulose esters, and polystyrene resins[1][2]. |
Invitro | 氢、碳和其他元素的稳定重同位素已被纳入药物分子中,主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注,因为它可能影响药物的药代动力学和代谢谱[1]。 |
Name | Mono(3-carboxypropyl) phthalate-d4 |
CAS | 1346600-69-8 |
Formula | C12H8D4O6 |
Molar Mass | 256.24 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Antonia M Calafat, et al. Mono-(3-carboxypropyl) phthalate, a metabolite of di-n-octyl phthalate. J Toxicol Environ Health A. 2006 Feb;69(3-4):215-27. [2]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-251. |