| Bioactivity | Mitoxantrone (dihydrochloride) (Standard) is the analytical standard of Mitoxantrone (dihydrochloride). This product is intended for research and analytical applications. Mitoxantrone dihydrochloride is a potent topoisomerase II inhibitor. Mitoxantrone dihydrochloride also inhibits protein kinase C (PKC) activity with an IC50 of 8.5 μM. Mitoxantrone dihydrochloride induces apoptosis of B-CLL (B-chronic lymphocytic leukaemia) cells. Mitoxantrone dihydrochloride shows antitumor activity. Mitoxantrone dihydrochloride also has anti-orthopoxvirus activity with EC50s of 0.25 μM and and 0.8 μM for cowpox and monkeypox, respectively. |
| CAS | 70476-82-3 |
| Formula | C₂₂H₃₀Cl₂N₄O₆ |
| Molar Mass | 517.40 |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Mitoxantrone dihydrochloride (Standard)
CAS: 70476-82-3 F: C₂₂H₃₀Cl₂N₄O₆ W: 517.40
Mitoxantrone (dihydrochloride) (Standard) is the analytical standard of Mitoxantrone (dihydrochloride). This product is
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This product is for research use only, not for human use. We do not sell to patients.