Bioactivity | Mioflazine dihydrochloride is a nucleoside transport inhibitor with sleep-improving activity. Mioflazine dihydrochloride significantly improves cardiac survival after global cardiac ischemia. Mioflazine dihydrochloride did not exhibit inotropic effects during induction and nursing. The pressure-volume curve of Mioflazine dihydrochloride after cardiac reperfusion was significantly better than that of the control group[1]. |
CAS | 83898-67-3 |
Formula | C29H32Cl4F2N4O2 |
Molar Mass | 648.40 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Wauquier A, et al. Sleep improvement in dogs after oral administration of mioflazine, a nucleoside transport inhibitor. Psychopharmacology (Berl). 1987;91(4):434-9. [2]. Mioflazine, a potentially protective drug against ischaemic damage: a study in dogs [3]. Pirovano IM, et al. Inhibition of nucleoside uptake in human erythrocytes by a new series of compounds related to lidoflazine and mioflazine. Eur J Pharmacol. 1990 Dec 15;189(6):419-22. |