| Bioactivity | Milvexian (BMS-986177), an effective antithrombotic agent, is an orally-bioavailable, reversible and direct inhibitor of human and rabbit factor XIa (FXIa) with Ki of 0.11, and 0.38 nM, respectively[1]. | ||||||||||||
| Name | Milvexian | ||||||||||||
| CAS | 1802425-99-5 | ||||||||||||
| Formula | C28H23Cl2F2N9O2 | ||||||||||||
| Molar Mass | 626.44 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
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| Reference | [1]. Wong P, et al. Small-Molecule Factor XIa Inhibitor, BMS-986177/JNJ-70033093, Prevents and Treats Arterial Thrombosis in Rabbits at Doses that Preserve Hemostasis [abstract]. Res Pract Thromb Haemost. 2020; 4 (Suppl 1). |
Milvexian
CAS: 1802425-99-5 F: C28H23Cl2F2N9O2 W: 626.44
Milvexian (BMS-986177), an effective antithrombotic agent, is an orally-bioavailable, reversible and direct inhibitor of
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