| Bioactivity | Microcystin-LY, a cyclic heptapeptide toxin from the cyanobacterium Microcystis aeruginosa[2], acts as an activator of the Nrf2 pathway to induce oxidative stress response, and the induction effect is most obvious at 3μM.[1]. |
| Target | Nrf2 |
| Name | Microcystin-LY |
| CAS | 123304-10-9 |
| Formula | C52H71N7O13 |
| Molar Mass | 1002.16 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Lundqvist J, et al. Microcystins activate nuclear factor erythroid 2-related factor 2 (Nrf2) in human liver cells in vitro - Implications for an oxidative stress induction by microcystins. Toxicon. 2017 Feb;126:47-50. [2]. Stoner RD, et al. The effects of single L-amino acid substitutions on the lethal potencies of the microcystins. Toxicon. 1989;27(7):825-8. |
Microcystin-LY
CAS: 123304-10-9 F: C52H71N7O13 W: 1002.16
Microcystin-LY, a cyclic heptapeptide toxin from the cyanobacterium Microcystis aeruginosa, acts as an activator of the
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