| Bioactivity | Microcolin H is a marine lipopeptide and phosphatidylinositol transfer protein ligand that targets PITPα/β. Microcolin H increases the conversion of LC3I to LC3II and reduces p62 levels in cancer cells, leading to autophagy cell death (Autophagy). Microcolin H effectively inhibits tumor development and has anti-proliferative activity in nude mouse subcutaneous tumor models[1]. |
| Target | Phosphatidylinositol transfer protein, PITPα/β |
| Name | Microcolin H |
| CAS | 2408008-21-7 |
| Formula | C38H63N5O9 |
| Molar Mass | 733.93 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Yang H et al. Microcolin H, a novel autophagy inducer, exerts potent antitumour activity by targeting PITPα/β. Signal Transduct Target Ther. 2023 Nov 15;8(1):428. |
Microcolin H
CAS: 2408008-21-7 F: C38H63N5O9 W: 733.93
Microcolin H is a marine lipopeptide and phosphatidylinositol transfer protein ligand that targets PITPα/β. Microcolin
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