| Bioactivity | Mezerein is a PKC activator that exhibits antileukemic properties. Mezerein inhibits the growth of yeast expressing PKC alpha (IC50=1190 nM), PKC beta1 (IC50=908 nM), and PKC delta (IC50=141 nM) but not of yeast expressing PKC[1][2]. |
| Invitro | Mezerein is an antileukemic principle isolated from Daphne mezereum L[2].Mezerein (50 ng/mL; 72 hours) potently inhibit tumorigenic murine macrophage cell line M5076 cellular proliferation[3]. Cell Proliferation Assay[3] Cell Line: |
| Name | Mezerein |
| CAS | 34807-41-5 |
| Formula | C38H38O10 |
| Molar Mass | 654.70 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |