| Bioactivity | Metixene (Piperidine) hydrochloride hydrate is an anticholinergic and antiparkinsonian agent. Metixene hydrochloride hydrate potently inhibits binding of quinuclidinyl benzilate (QNB) with the muscarinic receptor, IC50 and Ki values of 55 nM and 15 nM, respectively. Metixene hydrochloride hydrate can be used for the research of parkinsonian[1][2][3]. |
| Invitro | Metixene hydrochloride hydrate can potentially inhibit the binding of QNB with the muscarinic receptor， IC50 and Ki values of 55 nM and 15 nM, respectively[3]. |
| Name | Metixene hydrochloride hydrate |
| CAS | 7081-40-5 |
| Formula | C20H26ClNOS |
| Molar Mass | 363.94 |
| Appearance | Solid |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
| Reference | [1]. J. Hagenah, et al. Exogenous levodopa is not toxic to elderly subjects with non-parkinsonian movement disorders: further clinical evidence. , 106(3-4), 301–307. doi:10.1007/s007020050159 [2]. S L Levin, et al. Dualism in the effect of cholinolytics upon the human parotid gland deprived of parasympathetic control. Int J Clin Pharmacol Res. 1986;6(5):429-39. |
Metixene hydrochloride hydrate
CAS: 7081-40-5 F: C20H26ClNOS W: 363.94
Metixene (Piperidine) hydrochloride hydrate is an anticholinergic and antiparkinsonian agent. Metixene hydrochloride hyd
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