Bioactivity | Methylsolfonyl 25(S)-Δ7-dafachronic acid (compound 3) is a selective ssDAF-12 agonist with the IC50 of 0.41 μM. Methylsolfonyl 25(S)-Δ7-dafachronic acid shows low cell cytotoxicity in HepG2 cells with IC50 of >200 μM. Methylsolfonyl 25(S)-Δ7-dafachronic acid can be used for study of parasitism[1]. |
Formula | C28H45NO4S |
Molar Mass | 491.73 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Ceccarelli G, et al. Discovery and Structure-Activity Relationships of Novel ssDAF-12 Receptor Modulators. J Med Chem. 2024 Feb 28. |