Bioactivity | Methylprednisolone succinate is a synthetic glucocorticoid and widely used as an anti-inflammatory agent. |
Target | glucocorticoid receptor |
Name | Methylprednisolone succinate |
CAS | 2921-57-5 |
Formula | C26H34O8 |
Molar Mass | 474.54 |
Appearance | Solid |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | 4°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) |
Reference | [1]. Marchant A, et al. Methylprednisolone differentially regulates IL-10 and tumour necrosis factor (TNF) productionduring murine endotoxaemia. Clin Exp Immunol. 1996 Oct;106(1):91-6. [2]. Diem R, et al. Methylprednisolone increases neuronal apoptosis during autoimmune CNS inflammation by inhibition of an endogenous neuroprotective pathway. J Neurosci. 2003 Aug 6;23(18):6993-7000. |