Bioactivity | Methyl vanillate-d3 is deuterated labeled β-Phellandrene (HY-N8573). β-Phellandrene is obtained from Carum petroselinum. β-Phellandrene can be used to essential oil additives[1]. |
Invitro | 氢、碳和其他元素的稳定重同位素已被纳入药物分子中,主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注,因为它可能影响药物的药代动力学和代谢谱[1]。Methyl vanillate (0-100 μM) 增加颅骨成骨细胞中 β-catenin 的表达和核转位。Methyl vanillate 剂量依赖性地提高颅骨成骨细胞中的 ALP 活性[2]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> Methyl vanillate-d3 相关抗体: |
CAS | 1394230-40-0 |
Formula | C9H7D3O4 |
Molar Mass | 185.19 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Cha PH, et al. Hovenia dulcis Thunb extract and its ingredient methyl vanillate activate Wnt/β-catenin pathway and increase bone mass in growing or ovariectomized mice. PLoS One. 2014 Jan 22;9(1):e85546. |