Methyl brevifolincarboxylate_product_DataBase

Bioactivity	Methyl brevifolincarboxylate (Brevifolincarboxylic acid methyl ester) is a potent influenza virus PB2 cap-binding inhibitor. Methyl brevifolincarboxylate has anti-oxidant activity. Methyl brevifolincarboxylate also inhibits platelet aggregation, lipid metabolism and inflammation[1][2][4][5][6].
Invitro	Methyl brevifolincarboxylate 具有显着的 DPPH 自由基清除活性，IC50 值为 8.9 μM[2]。Methyl brevifolincarboxylate (10 和 30 μM) 抑制 LPS 刺激的巨噬细胞中 NO 和 TNF-α 的产生[2]。Methyl brevifolincarboxylate (1 和 10 μM) 抑制去甲肾上腺素 (Norepinephrine (HY-13715)) 诱导的大鼠主动脉收缩[3]。Methyl brevifolincarboxylate (5 μM) 抑制血小板聚集达 73.5%[4]。Methyl brevifolincarboxylate 对流感病毒 A/Puerto Rico/8/34 (H1N1) 和 A/Aichi/2/68 (H3N2) 有抑制作用，IC50 分别为 27.16 μM 和 33.41 μM[5]。Methyl brevifolincarboxylate (10-80 μM，48 小时) 降低 OA 处理的 SK-HEP-1 细胞和原代小鼠肝细胞中的 TG 水平[6]。 Cell Viability Assay[6] Cell Line:
Name	Methyl brevifolincarboxylate
CAS	154702-76-8
Formula	C14H10O8
Molar Mass	306.22
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.

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