Bioactivity | Methyl acetimidate is an imidoester that can inhibit the formation of sickle cells. Methyl acetimidate enhances the oxygen affinity and gelling properties of high molecular weight hemoglobin (HMW Hb) by modifying the amino groups of hemoglobin, thereby suppressing the formation of sickle cells. Methyl acetimidate can be used in research related to anemia[1]. |
CAS | 14777-29-8 |
Formula | C3H7NO |
Molar Mass | 73.09 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Chao TL, et al. Inhibition of sickling by methyl acetimidate. FEBS Lett. 1976 Feb 1;62(1):57-9. doi: 10.1016/0014-5793(76)80015-4. [2]. Chao TL, et al. The effects of oxygen affinity and gelation of hemoglobin S crosslinked by reaction with methyl acetimidate. Hemoglobin. 1981;5(1):47-72. |