| Bioactivity | Methyl 2-(7-hydroxy-2-oxo-2H-chromen-4-yl)acetate, a natural coumarins derivative, is exploited for the synthesis of the switchable fluorescent substrates to be used in bacterial enzyme detection[1][2][3]. |
| Invitro | Methyl 2-(7-hydroxy-2-oxo-2H-chromen-4-yl)acetate (compound 2) exhibits the maximum absorption (λabs~322 nm) and emission (λem~387 nm) wavelengths[2]. |
| Name | Methyl 2-(7-hydroxy-2-oxo-2H-chromen-4-yl)acetate |
| CAS | 15991-13-6 |
| Formula | C12H10O5 |
| Molar Mass | 234.20 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Nascimento JSD, et al. Mapping the Biotransformation of Coumarins through Filamentous Fungi. Molecules. 2019 Sep 29;24(19). [2]. Lizzul-Jurse A, et al. Readily functionalizable phosphonium-tagged fluorescent coumarins for enhanced detection of conjugates by mass spectrometry. Org Biomol Chem. 2016 Aug 10;14(32):7777-91. [3]. Giovannini G, et al. Coumarin-based, switchable fluorescent substrates for enzymatic bacterial detection. Talanta. 2018 Oct 1;188:448-453. |
Methyl 2-(7-hydroxy-2-oxo-2H-chromen-4-yl)acetate
CAS: 15991-13-6 F: C12H10O5 W: 234.20
Methyl 2-(7-hydroxy-2-oxo-2H-chromen-4-yl)acetate, a natural coumarins derivative, is exploited for the synthesis of the
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