Methoxyamine-d3 (Hydrochloride)_product_DataBase

Bioactivity	Methoxyamine-d3 (Hydrochloride) is the deuterium labeled Methoxyamine hydrochloride[1]. Methoxyamine (O-Methylhydroxylamine) hydrochloride is a reagent in the preparation of O-methyl oximes or synthesis of O-methyl oximes from aldehydes[2].
Invitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
Name	Methoxyamine-d3 (Hydrochloride)
CAS	110220-55-8
Formula	CH3D3ClNO
Molar Mass	86.54
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Sear JW, et al. Plasma concentrations of alphaxalone by gas chromatography: comparison with other gas chromatographic methods and gas chromatography-mass spectrometry. J Pharm Pharmacol. 1980 May;32(5):349-52.

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