| Bioactivity | Methoxy-X04 is a fluorescent dye that crosses the blood-brain barrier and selectively binds to beta-pleated sheets found in dense core amyloid Aβ plaques. |
| Name | Methoxy-X04 |
| CAS | 863918-78-9 |
| Formula | C23H20O3 |
| Molar Mass | 344.40 |
| Appearance | Solid |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) |
| Reference | [1]. Klunk WE, Bacskai BJ, Mathis CA, et al. Imaging Abeta plaques in living transgenic mice with multiphoton microscopy and methoxy-X04, a systemically administered Congo red derivative. J Neuropathol Exp Neurol. 2002;61(9):797-805. doi:10.1093/jnen/61.9.797 [2]. Bisht K, El Hajj H, Savage JC, Sánchez MG, Tremblay MÈ. Correlative Light and Electron Microscopy to Study Microglial Interactions with β-Amyloid Plaques. J Vis Exp. 2016;(112):54060. Published 2016 Jun 1. |
Methoxy-X04
CAS: 863918-78-9 F: C23H20O3 W: 344.40
Methoxy-X04 is a fluorescent dye that crosses the blood-brain barrier and selectively binds to beta-pleated sheets found
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