Bioactivity | Methoxy-PMS (1-Methoxy PMS), an active oxygen formation inducer, is stable electron-transport mediator between NAD(P)H and tetrazolium dyes[1][2]. |
Invitro | Methoxy-PMS has no cytotoxicity in the cell culture media. Methoxy-PMS receives an electron from NADH or NADPH at the membrane or inside of the cell and passes the electron to the WST-8 that is around the outer cell membrane[2]. |
Name | Methoxy-PMS |
CAS | 65162-13-2 |
Formula | C15H16N2O5S |
Molar Mass | 336.36 |
Appearance | Solid |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | 4°C, sealed storage, away from moisture and light *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light) |
Reference | [1]. De Niz M et al. Tools for mass screening of G6PD deficiency: validation of the WST8/1-methoxy-PMS enzymatic assay in Uganda.Malar J. 2013 Jun 19;12:210. [2]. Arakawa H et al. Chemiluminescence assay for tetrahydrobiopterin based on the generation of hydrogen peroxide using isoluminol-microperoxidase in the presence of 1-methoxy PMS. Luminescence. 2007 May-Jun;22(3):245-50. |