PeptideDB

Methotrexate-γ-aspartate

CAS: 64801-58-7 F: C24H27N9O8 W: 569.53

Methotrexate-γ-aspartate is a Ll210 cell dihydrofolate reductase inhibitor. Methotrexate-γ-aspartate is apparently mor
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Bioactivity Methotrexate-γ-aspartate is a Ll210 cell dihydrofolate reductase inhibitor. Methotrexate-γ-aspartate is apparently more resistant to enzymic cleavage than is methotrexate-y-glutamate. Methotrexate-γ-aspartate is promising for research of leukemic[1].
CAS 64801-58-7
Formula C24H27N9O8
Molar Mass 569.53
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Sirotnak FM, et al. Growth inhibitory, transport and biochemical properties of the gamma-glutamyl and gamma-aspartyl peptides of methotrexate in L1210 leukemia cells in vitro. Biochem Pharmacol. 1978;27(14):1821-5.