Bioactivity | Methotrexate-γ-aspartate is a Ll210 cell dihydrofolate reductase inhibitor. Methotrexate-γ-aspartate is apparently more resistant to enzymic cleavage than is methotrexate-y-glutamate. Methotrexate-γ-aspartate is promising for research of leukemic[1]. |
CAS | 64801-58-7 |
Formula | C24H27N9O8 |
Molar Mass | 569.53 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Sirotnak FM, et al. Growth inhibitory, transport and biochemical properties of the gamma-glutamyl and gamma-aspartyl peptides of methotrexate in L1210 leukemia cells in vitro. Biochem Pharmacol. 1978;27(14):1821-5. |