| Bioactivity | Metesind glucuronate (AG 331) is an inhibitor for thymidylate synthase with Ki of 1.2 nM. Metesind glucuronate inhibits the DNA synthesis and thus inhibits the cell viability of cancer cells with IC50 of 0.4-0.9 μM[1]. |
| CAS | 157182-23-5 |
| Formula | C29H34N4O10S |
| Molar Mass | 630.67 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Li WY, et al., High-performance liquid chromatographic method for the determination of a novel thymidylate synthase inhibitor, AG 331, in human serum. J Chromatogr B Biomed Appl. 1995 Nov 17;673(2):281-8. |
Metesind glucuronate
CAS: 157182-23-5 F: C29H34N4O10S W: 630.67
Metesind glucuronate (AG 331) is an inhibitor for thymidylate synthase with Ki of 1.2 nM. Metesind glucuronate inhibits
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