PeptideDB

Metelimumab

CAS: 272780-74-2 F: W:

Metelimumab (CAT-192) is a human IgG4 monoclonal antibody that can selectively neutralize TGFβ1.
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Bioactivity Metelimumab (CAT-192) is a human IgG4 monoclonal antibody that can selectively neutralize TGFβ1[1].
Target TGFβ1
Invitro Metelimumab (0.5 pg/mL-50 μg/mL) inhibits TGFβ1-stimulated IL-11 production in an A549 cell[1].
Name Metelimumab
CAS 272780-74-2
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Lord DM, et, al. Structure-based engineering to restore high affinity binding of an isoform-selective anti-TGFβ1 antibody. MAbs. 2018 Apr;10(3):444-452.