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Metaproterenol-d7-1 hemisulfate

CAS: F: C11H12D7NO7S W: 316.38

Metaproterenol-d7-1 (hemisulfate) is deuterium labeled Metaproterenol (hemisulfate). Metaproterenol hemisulfate (Orcipre
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This product is for research use only, not for human use. We do not sell to patients.

Bioactivity Metaproterenol-d7-1 (hemisulfate) is deuterium labeled Metaproterenol (hemisulfate). Metaproterenol hemisulfate (Orciprenaline hemisulfate) is a direct-acting sympathomimetic and a β2-adrenergic receptor (β2AR) agonist with an IC50 of 68 nM. Metaproterenol hemisulfate also has anti-inflammatory activity[1][2].
Formula C11H12D7NO7S
Molar Mass 316.38
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Noh H, et al. Beta 2-adrenergic receptor agonists are novel regulators of macrophage activation in diabetic renal and cardiovascular complications. Kidney Int. 2017 Jul;92(1):101-113. [3]. Ibrahim FA, et al. Highly sensitive spectrofluorimetric method for rapid determination of orciprenaline in biological fluids and pharmaceuticals. Luminescence. 2019 Feb;34(1):77-83.