| Bioactivity | Metaphit is a specific PCPantagonist and site-directed acylating agent of the [3H]phencyclidine binding site in rat brain homogenates[1]. Metaphit prevents PCP-induced locomotor behavior through presynaptic mechanisms[2]. |
| Name | Metaphit |
| CAS | 96316-00-6 |
| Formula | C18H24N2S |
| Molar Mass | 300.46 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. E D French, et al. Metaphit, a proposed phencyclidine (PCP) antagonist, prevents PCP-induced locomotor behavior through mechanisms unrelated to specific blockade of PCP receptors. Eur J Pharmacol. 1987 Aug 21;140(3):267-74 [2]. M F Rafferty, et al. A specific acylating agent for the [3H]phencyclidine receptors in rat brain. FEBS Lett. 1985 Feb 25;181(2):318-22. |