| Bioactivity | Metaphit methylsulfate is a specific PCP antagonist and site-directed acylating agent of the [3H]phencyclidine binding site in rat brain homogenates. Metaphit methylsulfate prevents PCP-induced locomotor behavior through presynaptic mechanisms[1][2]. |
| CAS | 99287-12-4 |
| Formula | C19H28N2O3S2 |
| Molar Mass | 396.57 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. E D French, et al. Metaphit, a proposed phencyclidine (PCP) antagonist, prevents PCP-induced locomotor behavior through mechanisms unrelated to specific blockade of PCP receptors. Eur J Pharmacol. 1987 Aug 21;140(3):267-74 [2]. M F Rafferty, et al. A specific acylating agent for the [3H]phencyclidine receptors in rat brain. FEBS Lett. 1985 Feb 25;181(2):318-22. |
Metaphit methylsulfate
CAS: 99287-12-4 F: C19H28N2O3S2 W: 396.57
Metaphit methylsulfate is a specific PCP antagonist and site-directed acylating agent of the phencyclidine binding site
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