| Bioactivity | Metamizol (Methamizole) is an anti-thyroid agent, which blocks thyroid hormone production from the thyroid gland. Metamizol can cause hepatotoxicity[1]. |
| In Vivo | Metamizo (Methamizole; 100 mg/kg; i.p.; once; male Swiss albino mice) causes hepatotoxicity as revealed by an increase in serum alanine aminotransferase (ALT) activity[1].Metamizo (100 mg/kg; i.p.; once; male Swiss albino mice) causes a decrease in hepatic glutathione (GSH) contents[1]. Animal Model: |
| Name | Metamizol |
| CAS | 50567-35-6 |
| Formula | C13H17N3O4S |
| Molar Mass | 311.36 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Heidari R, et, al. Effects of Enzyme Induction and/or Glutathione Depletion on Methimazole-Induced Hepatotoxicity in Mice and the Protective Role of N-Acetylcysteine. Adv Pharm Bull. 2014;4(1):21-8. |
Metamizol
CAS: 50567-35-6 F: C13H17N3O4S W: 311.36
Metamizol (Methamizole) is an anti-thyroid agent, which blocks thyroid hormone production from the thyroid gland. Metami
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