| Bioactivity | Metallo-β-lactamase-IN-3 (compound 35) is a potent metallo-β-lactamases (MBL) inhibitor. Metallo-β-lactamase-IN-3 shows high activity against VIM-1 and NDM-1, with IC50 of 0.6 and 1.0 μM, respectively. Metallo-β-lactamase-IN-3 does not show inhibition of IMP-7[1]. |
| Target | IC50: 0.6 ± 0.0 μM (VIM-1), 1.0 ± 0.4 μM (NDM-1), > 10 μM (IMP-7) |
| Name | Metallo-β-lactamase-IN-3 |
| CAS | 128294-71-3 |
| Formula | C10H11NO3S |
| Molar Mass | 225.26 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Kaya C, et al. N-Aryl Mercaptopropionamides as Broad-Spectrum Inhibitors of Metallo-β-Lactamases. J Med Chem. 2022 Mar 10;65(5):3913-3922. |
Metallo-β-lactamase-IN-3
CAS: 128294-71-3 F: C10H11NO3S W: 225.26
Metallo-β-lactamase-IN-3 (compound 35) is a potent metallo-β-lactamases (MBL) inhibitor. Metallo-β-lactamase-IN-3 sho
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.