Mesotrione_product_DataBase

Bioactivity	Mesotrione is a herbicide belongs to the benzoylcyclohexanedione family. Mesotrione is a potent and competitive and reversible inhibitor of HPPD enzyme. Mesotrione is selective to maize due to rapid metabolism and relative high tolerance by the susceptible crop plant[1].
Target	Target: HPPD enzyme
Invitro	Mesotrione is a potent HPPD enzyme inhibitor, giving an estimated Ki value in the range 6±18pM at 25°C. HPPD is from Arabidopsis thaliana (L)[1].
In Vivo	Mesotrione (oral administration; 1 mg/kg; single dose) is rapidly and extensively absorbed in rats and mice. After a single dose, the urinary excretione is estimated, the urinary excretione estimated absorption values ranged from 62.2% in males and 68.3% in females. The mean peak blood concentration (Cmax) of radioactivity occurred 0.5 hours after dosing in each sex[1].
Name	Mesotrione
CAS	104206-82-8
Formula	C14H13NO7S
Molar Mass	339.32
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. G Mitchell, et al. Mesotrione: A New Selective Herbicide for Use in Maize.Pest Manag Sci.2001 Feb;57(2):120-8. [2]. CLH report.Proposal for Harmonised Classification and Labelling.Based on Regulation (EC) No 1272/2008 (CLP Regulation), Annex VI, Part 2.Substance Name: Mesotrione

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