| Bioactivity | Menin-MLL inhibitor 34 (Compound 37) is a selective and potent Menin-MLL inhibitor, with an IC50 of 18.21 nM for Menin. Menin-MLL inhibitor 34 has long-lasting anti-leukemic effects by reducing Menin protein levels and down-regulating MEN1 transcription[1]. |
| Formula | C40H54FN9O4S |
| Molar Mass | 775.98 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Luo M, et al. Design and development of a series of 4-(piperazin-1-yl)pyrimidines as irreversible menin inhibitors. Eur J Med Chem. 2024 Sep 30;280:116918. |
Menin-MLL inhibitor 34
CAS: F: C40H54FN9O4S W: 775.98
Menin-MLL inhibitor 34 (Compound 37) is a selective and potent Menin-MLL inhibitor, with an IC50 of 18.21 nM for Menin.
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