Bioactivity | Meliadubin B is a natural triterpenoid with significant inflammatory inhibition effect toward superoxide anion generation in human neutrophils (EC50 of 5.54 μM). Meliadubin B inhibits inducible nitric oxide synthase. Meliadubin B shows remarkable inhibition against the rice pathogenic fungus Magnaporthe oryzae with IC50 of 182.50 μM. |
Name | Meliadubin B |
Formula | C30H48O4 |
Molar Mass | 472.70 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Hieu Tran Trung, et al. Anti-inflammatory and Antiphytopathogenic Fungal Activity of 2,3- seco-Tirucallane Triterpenoids Meliadubins A and B from Melia dubia Cav. Barks with ChemGPS-NP and In Silico Prediction. ACS Omega. 2023 Sep 27;8(40):37116-37127. |