Bioactivity | Melatonin receptor agonist 1 (compound 20c) is a potent melatonin receptor (MT) agonist, with Ki values of 108 nM (MT2) and 1140 nM (MT1)[1]. |
Invitro | Melatonin receptor agonist 1 (compound 20c) shows a 10 times MT2-selectivity over MT1[1]. |
Name | Melatonin receptor agonist 1 |
CAS | 2411150-76-8 |
Formula | C15H19N3O2 |
Molar Mass | 273.33 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Bolteau R, et al. Quinazoline and phthalazine derivatives as novel melatonin receptor ligands analogues of agomelatine. Eur J Med Chem. 2020 Mar 1;189:112078. |