PeptideDB

Melanostatin, frog

CAS: 134709-16-3 F: C189H285N53O57S W: 4243.67

Melanostatin, frog is an inhibitor for α-melanocyte-stimulating hormone (α-MSH) release, with an IC50 of 60 nM.
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This product is for research use only, not for human use. We do not sell to patients.

Bioactivity Melanostatin, frog is an inhibitor for α-melanocyte-stimulating hormone (α-MSH) release, with an IC50 of 60 nM[1][2].
Invitro Melanostatin, frog (1 μM) 增加钾电流,降低钠电流和钙电流,从而使细胞膜超极化[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> Melanostatin, frog 相关抗体:
CAS 134709-16-3
Sequence Tyr-Pro-Ser-Lys-Pro-Asp-Asn-Pro-Gly-Glu-Asp-Ala-Pro-Ala-Glu-Asp-Met-Ala-Lys-Tyr-Tyr-Ser-Ala-Leu-Arg-His-Tyr-Ile-Asn-Leu-Ile-Thr-Arg-Gln-Arg-Tyr-NH2
Shortening YPSKPDNPGEDAPAEDMAKYYSALRHYINLITRQRY-NH2
Formula C189H285N53O57S
Molar Mass 4243.67
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Valentijn JA, et al., Melanostatin (NPY) inhibited electrical activity in frog melanotrophs through modulation of K+, Na+ and Ca2+ currents. J Physiol. 1994 Mar 1;475(2):185-95. [2]. Chartrel N, et al., Characterization of melanotropin-release-inhibiting factor (melanostatin) from frog brain: homology with human neuropeptide Y. Proc Natl Acad Sci U S A. 1991 May 1;88(9):3862-6.