| Bioactivity | Meclofenamic acid (Meclofenamate) is a non-steroidal anti-inflammatory agent. Meclofenamic acid is a highly selective FTO (fat mass and obesity-associated) enzyme inhibitor. Meclofenamic acid competes with FTO binding for the m(6)A-containing nucleic acid. Meclofenamic acid is a non-selective gap-junction blocker. Meclofenamic acid inhibits hKv2.1 and hKv1.1, with IC50 values of 56.0 and 155.9 μM, respectively[1][2][3][4]. |
| Invitro | Meclofenamic acid (0-100 μM, 24 h) inhibits FTO demethylation in a dose-response manner[1].Meclofenamic acid inhibits enzyme cyclooxygenase, with an IC50 about 1 μM, thereby inhibiting the production of prostaglandins[2].Meclofenamic acid inhibits the release of 5-HETE and LTB4 from human neutrophils stimulated with calcium ionophore and antagonizes the response of tissues to certain prostaglandins[2]. Western Blot Analysis[1] Cell Line: |
| Name | Meclofenamic acid |
| CAS | 644-62-2 |
| Formula | C14H11Cl2NO2 |
| Molar Mass | 296.15 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Meclofenamic acid
CAS: 644-62-2 F: C14H11Cl2NO2 W: 296.15
Meclofenamic acid (Meclofenamate) is a non-steroidal anti-inflammatory agent. Meclofenamic acid is a highly selective FT
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.