PeptideDB

MeOSuc-Ala-Ala-Pro-Val-pNA

CAS: 70967-90-7 F: C27H38N6O9 W: 590.63

MeOSuc-Ala-Ala-Pro-Val-pNA is a sensitive fluorogenic substrate of human leukocyte and porcine pancreatic elastase.
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Bioactivity MeOSuc-Ala-Ala-Pro-Val-pNA is a sensitive fluorogenic substrate of human leukocyte and porcine pancreatic elastase[1].
Invitro MeOSuc-Ala-Ala-Pro-Val-pNA exhibits kc/Km values of 185,000, 15,000, 58,000 and 330,000 M-1s-1 at 0.10 M phosphate, 0.20 M Mes, 0.10 M phosphate and 0.04 M phosphate, respectively, for reactions of human leukocyte elastase[2].
Name MeOSuc-Ala-Ala-Pro-Val-pNA
CAS 70967-90-7
Formula C27H38N6O9
Molar Mass 590.63
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Castillo MJ, et al. Sensitive substrates for human leukocyte and porcine pancreatic elastase: a study of the merits of various chromophoric and fluorogenic leaving groups in assays for serine proteases. Anal Biochem. 1979 Oct 15;99(1):53-64. [2]. Ross L. Stein, et al. Catalysis by human leukocyte elastase. Rate-limiting deacylation for specific p-nitroanilides and amides. J. Am. Chem. Soc. 1984, 106, 3, 796-798.