| Bioactivity | MeOSuc-AAPV-CMK (Elastase Inhibitor III) is an elastase inhibitor. MeOSuc-AAPV-CMK also inhibits cathepsin G and proteinase 3.MeOSuc-AAPV-CMK blocks the cleavage of adiponectin by leukocyte elastase[1]. |
| Name | MeOSuc-AAPV-CMK |
| CAS | 65144-34-5 |
| Sequence | {MeOSuc}-Ala-Ala-Pro-Val-{CMK} |
| Shortening | {MeOSuc}-AAPV-{CMK} |
| Formula | C22H35ClN4O7 |
| Molar Mass | 502.99 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Waki H, et al. Generation of globular fragment of adiponectin by leukocyte elastase secreted by monocytic cell line THP-1. Endocrinology. 2005 Feb;146(2):790-6. [2]. Middelhoven PJ, Vet al. Different proteolytic mechanisms involved in Fc gamma RIIIb shedding from human neutrophils. Clin Exp Immunol. 2001 Jul;125(1):169-75. |