| Bioactivity | Mca-SEVKMDAEFRK(Dnp)RR-NH2, containing the wild-type amyloid precursor protein (APP) beta-secretase cleavage site, is the substrate of thimet oligopeptidase (TOP). It is used for Alzheimer's disease research[1]. |
| Target | others |
| Name | Mca-SEVKMDAEFRK(Dnp)RR-NH2 |
| CAS | 1802078-33-6 |
| Sequence | {Mca}-Ser-Glu-Val-Lys-Met-Asp-Ala-Glu-Phe-Arg-{Lys(Dnp)}-Arg-Arg-NH2 |
| Shortening | {Mca}-SEVKMDAEFR-{Lys(Dnp)}-RR-NH2 |
| Formula | C87H129N27O28S |
| Molar Mass | 2033.18 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. H Koike, et al. Thimet Oligopeptidase Cleaves the Full-Length Alzheimer Amyloid Precursor Protein at a β-Secretase Cleavage Site in COS Cells. J Biochem. 1999 Jul;126(1):235-42. |
Mca-SEVKMDAEFRK(Dnp)RR-NH2
CAS: 1802078-33-6 F: C87H129N27O28S W: 2033.18
Mca-SEVKMDAEFRK(Dnp)RR-NH2, containing the wild-type amyloid precursor protein (APP) beta-secretase cleavage site, is th
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