| Bioactivity | Mca-KPLGL-Dap(Dnp)-AR-NH2 TFA is a fluorogenic substrate for matrix metalloproteinases (MMPs). 7-methoxycoumarin-4 acetyl (Mac) is released and its fluorescence can be used to quantify MMP activity. Mac displays Ex/Em of 328/420 nm[1]. |
| CAS | 1392300-20-7 |
| Sequence | {Mca}-Lys-Pro-Leu-Gly-Leu-{Dap(Dnp)}-Ala-Arg-NH2 |
| Shortening | {Mca}-KPLGL-{Dap(Dnp)}-AR-NH2 |
| Formula | C57H81F3N16O18 |
| Molar Mass | 1335.34 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Ulf Neumann, et al. Characterization of Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2, a fluorogenic substrate with increased specificity constants for collagenases and tumor necrosis factor converting enzyme. Comparative Study Anal Biochem. 2004 May 15;328(2):166-73. |
Mca-KPLGL-Dap(Dnp)-AR-NH2 TFA
CAS: 1392300-20-7 F: C57H81F3N16O18 W: 1335.34
Mca-KPLGL-Dap(Dnp)-AR-NH2 TFA is a fluorogenic substrate for matrix metalloproteinases (MMPs). 7-methoxycoumarin-4 acety
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