| Bioactivity | McN-A-343 is a selective M1 muscarinic agonist that stimulates muscarinic transmission in sympathetic ganglia. McN-A-343 reduces inflammation and oxidative stress in an experimental model of ulcerative colitis[1][2]. | ||||||||||||
| Name | McN-A-343 | ||||||||||||
| CAS | 55-45-8 | ||||||||||||
| Formula | C14H18Cl2N2O2 | ||||||||||||
| Molar Mass | 317.21 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
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| Reference | [1]. Koss MC, et al. Analysis of miosis produced by McN-A-343 in anesthetized cats. J Ocul Pharmacol Ther. 1995;11(3):389-399. [2]. Magalhães DA, Batista JA, Sousa SG, et al. McN-A-343, a muscarinic agonist, reduces inflammation and oxidative stress in an experimental model of ulcerative colitis. Life Sci. 2021;272:119194. |
McN-A-343
CAS: 55-45-8 F: C14H18Cl2N2O2 W: 317.21
McN-A-343 is a selective M1 muscarinic agonist that stimulates muscarinic transmission in sympathetic ganglia. McN-A-343
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