| Bioactivity | Mc-Val-Cit-PAB-Cl is a cleavable ADC linker. Mc-Val-Cit-PAB-Cl can be used to conjugate MMAE and antibody to form antibody-MC-vc-MMAE (e.g., anti-CD22-MC-VC-PABC-MMAE with IC50s of 3.3 and 0.95 nM for BJAB and WSU cell lines in cytotoxicity assay). |
| Name | Mc-Val-Cit-PAB-Cl |
| CAS | 1639351-92-0 |
| Formula | C28H39ClN6O6 |
| Molar Mass | 591.10 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | -20°C, stored under nitrogen *In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen) |
Mc-Val-Cit-PAB-Cl
CAS: 1639351-92-0 F: C28H39ClN6O6 W: 591.10
Mc-Val-Cit-PAB-Cl is a cleavable ADC linker. Mc-Val-Cit-PAB-Cl can be used to conjugate MMAE and antibody to form antibo
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