Bioactivity | Mc-Pro-PAB-MMAE is a Drug-Linker Conjugate for ADC. Mc-Pro-PAB-MMAE consists of Monomethyl auristatin E (HY-15162) and a linker. Mc-Pro-PAB-MMAE can be used for synthesis of ADCs[1][2]. |
CAS | 2766450-03-5 |
Formula | C64H95N9O14 |
Molar Mass | 1214.49 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Ilaria BIANCOFIORE, et al. Fibroblast activation protein ligands for targeted delivery applications. Patent, WO2021160825, 2021-08-19. [2]. Bocci M, et al. In vivo activation of FAP-cleavable small molecule-drug conjugates for the targeted delivery of camptothecins and tubulin poisons to the tumor microenvironment[J]. Journal of Controlled Release, 2024, 367: 779-790. |