Bioactivity | Maytansine is a highly potent microtubule-targeted compound that induces mitotic arrest and kills tumor cells at subnanomolar concentrations[1]. | ||||||||||||
Invitro | Maytansine, at 6x10-8 M, irreversibly inhibits cell division in eggs of sea urchins and clams. Maytansine causes the disappearance of a mitotic apparatus or prevents one from forming if added at early stages. Maytansine inhibits in vitro polymerization of tubulin[2]. | ||||||||||||
Name | Maytansine | ||||||||||||
CAS | 35846-53-8 | ||||||||||||
Formula | C34H46ClN3O10 | ||||||||||||
Molar Mass | 692.20 | ||||||||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
Storage |
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