| Bioactivity | Maydispenoid B is a potent immunosuppressor. Maydispenoid B can inhibit anti-CD3/anti-CD28 mAbs activated and lipopolysaccharide activated murine splenocyte proliferation[1]. |
| Invitro | Maydispenoid B (compound 3) exhibits potential inhibitory activity in anti-CD3/anti-CD28 monoclonal antibodies (mAbs) stimulated murine splenocytes proliferation, with an IC50 value of 9.38 μM, respectively[1].Maydispenoid B suppresses the murine splenocytes proliferation activated by lipopolysaccharide (LPS), with an IC50 value of 16.82 μM, respectively[1]. |
| Name | Maydispenoid B |
| Formula | C25H34O4 |
| Molar Mass | 398.54 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Duan X, et al. New secondary metabolites with immunosuppressive activity from the phytopathogenic fungus Bipolaris maydis. Bioorg Chem. 2020 Jun;99:103816. |