Bioactivity | Martinostat (hydrochloride) is a inhibitor of HDAC that can be labeled with radionuclides for diagnostic applications[1][2]. |
Name | Martinostat hydrochloride |
Formula | C22H31ClN2O2 |
Molar Mass | 390.95 |
Appearance | 固体 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | 4°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
Reference | [1]. Changning Wang, et al. In Vivo Imaging of Histone Deacetylases (HDACs) in the Central Nervous System and Major Peripheral Organs. J Med Chem. 2014 Oct 9;57(19):7999-8009. [2]. Tharick A Pascoal, et al. [11C]Martinostat PET analysis reveals reduced HDAC I availability in Alzheimer’s disease. Nat Commun. 2022 Jul 19;13(1):4171. |