| Bioactivity | Manool is a diterpene from Salvia officinalis. Manool induces selective cytotoxicity in cancer cells. Manool arrests the cancer cells at the G(2)/M phase of the cell cycle[1][2]. |
| Invitro | Manool exhibits higher cytotoxic activity against HeLa (IC50=6.7 µg/mL) and U343 (IC50=6.7 µg/mL) cells[1].Manool exhibits a protective effect against chromosome damage induced by MMS in HepG2 cells[3]. |
| Name | Manool |
| CAS | 596-85-0 |
| Formula | C20H34O |
| Molar Mass | 290.48 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, stored under nitrogen *In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen) |