Bioactivity | Mannosamine-desthiobiotin adduct (compound MDTBA) is a carrier immunogenicity-reducing hapten that reduces the immunogenicity of protein carriers upon conjugation to available free amines on the carrier protein surface. Conjugation of Mannosamine-desthiobiotin adduct to hsIgG significantly (>1-fold) reduced the immunogenicity of hsIgG. Mannosamine-desthiobiotin adduct can be used in antigen design research[1]. |
Name | Mannosamine–desthiobiotin adduct |
Formula | C16H29N3O7 |
Molar Mass | 375.42 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Gefen T, et al. The effect of haptens on protein-carrier immunogenicity. Immunology. 2015 Jan;144(1):116-26. |