| Bioactivity | Mal-amido-(CH2COOH)2, compound 7a, is a maleimidoethyl-containing intermediate for hydrophilic ADC linker[1]. | |||||||||
| Invitro | Mal-amido-(CH2COOH)2 is a intermediate for linker. Bivalent doxorubicin (DOX)-dipeptides (16a-c) are finally prepared and conjugated to the monoclonal antibody BR96. The dipeptides are cleaved by lysosomal proteases following internalization of the resulting immunoconjugates[1]. | |||||||||
| Name | Mal-amido-(CH2COOH)2 | |||||||||
| CAS | 207613-14-7 | |||||||||
| Formula | C11H12N2O7 | |||||||||
| Molar Mass | 284.22 | |||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | |||||||||
| Storage |
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