Bioactivity | Maculatin 1.1 TFA is an antimicrobial peptide with an MIC against Staphylococcus aureus of 7 μM. Maculatin 1.1 TFA can perforate the bacterial membrane of Staphylococcus aureus, causing bacterial death[1]. | ||||||
Name | Maculatin 1.1 TFA | ||||||
Sequence | Gly-Leu-Phe-Gly-Val-Leu-Ala-Lys-Val-Ala-Ala-His-Val-Val-Pro-Ala-Ile-Ala-Glu-His-Phe-NH2 | ||||||
Shortening | GLFGVLAKVAAHVVPAIAEHF-NH2 | ||||||
Formula | C103H161N27O23.xC2HF3O2 | ||||||
Molar Mass | 2145.55 (free base) | ||||||
Appearance | 固体 | ||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||
Storage | Sealed storage, away from moisture and light
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light) |
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Reference | [1]. Sani MA, et al. Maculatin 1.1 disrupts Staphylococcus aureus lipid membranes via a pore mechanism. Antimicrob Agents Chemother. 2013 Aug;57(8):3593-600. |