Bioactivity | Macrophage-activating lipopeptide 2 (MALP-2) is a lipopeptide Toll-like receptor TLR-2/6 agonist. Macrophage activating lipopeptide-2 (MALP-2) can enhance endothelial adhesion of white blood cells and improve perfusion recovery and collateral growth in the hind limbs of hypercholesterolemic Apoe deficient mice undergoing experimental femoral artery ligation (FAL)[1]. |
Invitro | Macrophage-activating lipopeptide 2 (MALP-2) (1 µg/mL, 24 h) 可以促进主要内皮粘附分子及白细胞整合素受体的表达,从而增强白细胞的内皮粘附[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> Macrophage-activating lipopeptide 2 相关抗体: RT-PCR[1]. Cell Line: |
In Vivo | Macrophage-activating lipopeptide 2 (MALP-2) (1 µg; 每天 1 次; 10 天; 静脉注射) 可以改善接受实验性股动脉结扎 (FAL) 的高胆固醇血症 Apoe 缺陷小鼠后肢的灌注恢复和侧支生长[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: |
CAS | 250718-44-6 |
Sequence | {S-[(2R)-2,3-bis[(1-oxohexadecyl)oxy]propyl]Cys}-Gly-Asn-Asn-Asp-Glu-Ser-Asn-Ile-Ser-Phe-Lys-Glu-Lys |
Shortening | {S-[(2R)-2,3-bis[(1-oxohexadecyl)oxy]propyl]Cys}-GNNDESNISFKEK |
Formula | C99H167N19O30S |
Molar Mass | 2135.56 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Troidl K, et al. The Lipopeptide MALP-2 Promotes Collateral Growth. Cells. 2020 Apr 16;9(4):997. |