Bioactivity | Macrocalin B is a diterpenoid, which can be isolated from Isodon xerophilus. Macrocalin B inhibits the proliferation of cancer cells K562, HL-60, A549, MKN, CA and HCT with IC50 of 2.81-171 μM. Macrocalin B inhibits the telomerase in K562 with an IC50 in nanomolar level[1]. |
CAS | 93781-75-0 |
Formula | C20H26O6 |
Molar Mass | 362.42 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Yang Y, et al., Effects of three diterpenoids on tumour cell proliferation and telomerase activity. Nat Prod Res. 2009;23(11):1007-12. |