| Bioactivity | MV1 is an antagonist of IAP (inhibitor of apoptosis protein), leads to protein knockdown of HaloTag-fused proteins when combined with HaloTag ligand[1]. | ||||||||||||
| Invitro | MV1 (0.08-20 μM; 24 h) inhibits the growth of EVSAT cells[1].MV1 (5 μM; 0-60 min) treatment causes rapid loss of c-IAP1 and c-IAP2 in MDA-MB-231 cells[1].MV1 (5 μM; 1 h) treatment inducing degradation of c-IAP1 and c-IAP2 is dependent on proteasomal machinery but not on caspase activation[1]. Cell Viability Assay[1] Cell Line: | ||||||||||||
| Name | MV1 | ||||||||||||
| CAS | 1001600-54-9 | ||||||||||||
| Formula | C33H44N4O5 | ||||||||||||
| Molar Mass | 576.73 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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